Riccardo Sabatini
Chief Data Scientist Orionis Biosciences LLC
Riccardo Sabatini is Chief Data Scientist at Orionis Biosciences, where he leads the application of artificial intelligence, computational genomics, and data science to drug discovery. A scientist and entrepreneur with expertise spanning physics, machine learning, and biotechnology, he has been a pioneer in AI-driven healthcare and precision medicine, helping accelerate the development of next-generation therapeutics.
Seminars
Wednesday 27th January 2027
Towards Full Expansion of Ligase Platforms
9:00 am
- Integrating artificial intelligence, robotics, and high-throughput experimentation to systematically identify productive induced-proximity events, accelerating molecular glue discovery at unprecedented scale
- Leveraging a purpose-built AI infrastructure designed specifically for molecular glue biology to uncover novel target-ligase relationships, expanding the searchable discovery landscape beyond traditional approaches
- Applying large-scale experimental and computational workflows to rapidly generate, validate, and prioritize molecular glue candidates, enabling faster progression from discovery to therapeutic development
Wednesday 27th January 2027
Panel Discussion: Can AI and Computational Methods Crack the Molecular Glue Code? Turning Predictions into Validated Hits
9:30 am
- How can AI-powered and computational approaches be used to identify gluable surfaces, target-ligase pairings, and novel molecular glue opportunities, while integrating target selection with the practical challenge of finding tractable gluable interfaces?
- How can the molecular glue field overcome limited datasets to improve model training, predictive accuracy, and biological relevance, enabling more reliable AI-driven discovery workflows?
- How can computational predictions be most effectively combined with experimental screening, structural biology, and validation strategies to accelerate hit identification and optimize molecular glue potency and selectivity?
