Aseem Ansari
Chair of the Department of Chemical Biology and Therapeutics St. Jude Children's Research Hospital
Seminars
Thursday 28th January 2027
Rewiring Gene Expression with Synthetic Gene Regulators to Access Previously Undruggable Biology
9:00 am
- Harnessing synthetic gene regulators to induce targeted DNA-protein interactions and reprogram gene expression, expanding induced-proximity therapeutics beyond protein degradation
- Developing modular transcription-targeting platforms to selectively control disease-driving gene networks, unlocking therapeutic opportunities against previously intractable targets
- Translating synthetic gene regulation from foundational discovery to clinical development through scalable design principles and emerging therapeutic programmes, broadening the future scope of induced-proximity medicine
