Modulation of Cancer Specific Interactomes via Chemical Switches & Molecular Glues

  • Explore how chemical switches and molecular glues can reprogram cellular signaling networks beyond traditional protein degradation approaches
  • Apply structure-based design strategies to harness chemically induced proximity for overcoming drug resistance and achieving ultra-selective kinase modulation
  • Demonstrate how precise modulation of cancer-specific interactomes can open new avenues for therapeutic discovery and innovation