From First-in-Human Studies to Clinical Validation: Advancing Non- Degrading Molecular Glues into Patients

3:30 pm - Wednesday 27th January 2027

  • Advancing a novel non-degrading molecular glue from discovery through clinical development, demonstrating how induced-proximity therapeutics can generate therapeutic benefit beyond protein degradation
  • Evaluating safety, pharmacokinetics, pharmacodynamic biomarkers, and early signals of activity from first-in-human studies to establish the clinical potential of nondegrading molecular glue therapies
  • Sharing key translational and clinical learnings from programme progression to help de-risk future molecular glue development efforts and accelerate the path from innovative biology to patient impact

Speakers:

Chief Medical Officer
Nested Therapeutics