Decoding Glueability: Finding Better Molecular Glue Targets Faster
10:00 am - Wednesday 27th January 2027
- Leveraging new platform systematically map target-ligase interactions and identify productive induced-proximity events, expanding access to previously undruggable proteins
- Integrating functional screening, proteomics, and mechanistic profiling to rapidly validate molecular glue hits, improving confidence in target engagement and downstream biological activity
- Applying a target-first discovery strategy to uncover novel degrader opportunities across challenging protein classes, enabling more efficient progression from target selection to therapeutic candidate
