Matthias Brand

Company: Proxygen GmbH

Job title: Chief Technology Officer

Seminars:

Panel Discussion: Interrogating the Properties & Characteristics of Molecular Glues to Develop the Most Effective Degraders 12:00 pm

As an industry, how should we define molecular glues going forward to establish great drug discovery and development opportunities that address unmet patient needs? What are the ideal properties of molecular glues that small molecules can be optimized towards? Where does a molecular glue end and a PROTAC begin? New CompanyRead more

day: Conference Day Two

Decoupling of Drug Exposure & Pharmacodynamics as an Opportunity for Spaced Out Dosing Schedules of Molecular Glues 2:30 pm

Exploring the pharmacodynamic effects of glue degraders that persist after drug clearance until the target protein is resynthesized Achieving long lasting effects on cellular signaling with short exposures to the degrader Spacing out administration of treatment as an option to consider for degrader programs New DataRead more

day: Conference Day Two