Andrew Potterton

Company: Adhesion Therapeutics

Job title: Head of Technology Platform

Seminars:

Panel Discussion: Spearheading Structure-Based Rational Design to Develop More Effective Molecular Glues 3:45 pm

What are the structural considerations between ligases, target proteins and molecular glues in rational design? How to overcome the difficulties in turning protein models from crystal structures to dynamic models What information do the different computational models give about the ternary complexes and how can this be leveraged in molecular glue design? New CompaniesRead more

day: Conference Day One

Turbocharging Computational Methods for Rational Design, Discovery & Property Prediction of Molecular Glues 9:01 am

Combining Machine Learning & Molecular Dynamics to Predict Protein-Protein Interactions for Molecular Glue Discovery How to use ML to find and rank undruggable targets for molecular glues Predicting druggable pockets for small molecules to computationally design molecular glues  Combining ML and molecular dynamics to increase success of glue virtual screens Diving into the Molecular Dynamics…Read more

day: Pre-Conference Day