Supercharging Discovery & Characterization of Molecular Glues Using High-Purity FRET-Active E2-Ubiquitin Conjugates
Time: 9:30 am
day: Conference Day One
Details:
- Accurate measurement of ubiquitin transfer rates offers unprecedented insight into molecular glue-induced proximity of ligases and substrate proteins
- Real-time, high-sensitivity fluorescent assays offer a path for high-throughput discovery and characterization of molecular glues
- How gluey is your glue? Accurate measurement of binding affinities at all intermolecular interfaces illuminates energetics or ternary complex assembly
New Data
