Decoupling of Drug Exposure & Pharmacodynamics as an Opportunity for Spaced Out Dosing Schedules of Molecular Glues
Time: 2:30 pm
day: Conference Day Two
Details:
- Exploring the pharmacodynamic effects of glue degraders that persist after drug clearance until the target protein is resynthesized
- Achieving long lasting effects on cellular signaling with short exposures to the degrader
- Spacing out administration of treatment as an option to consider for degrader programs
New Data