Wu Du
Senior Vice President - Medicinal Chemistry Hinova
Dr. Du received PhD in organic chemistry from the University of Pittsburgh. After postdoc in the Scripps Research Institute, he joined Merck, then later PTC Therapeutics as a medicinal chemist. Dr. Du delivered multiple small molecules, including inhibitors, agonist, oral PROTAC degraders, molecular glue degrader as PCCs and into clinical development. Currently he is SVP of medchem in Hinova Pharma.
Seminars
Wednesday 28th January 2026
Discovery of Novel VAV1 Molecular Glue Degrader with Superior Potency & Efficacy
4:00 pm
- VAV1 is an emerging first in class target for a broad range of autoimmune and inflammatory diseases
- Discovery a class of orally available VAV1 degrader with a novel scaffold
- Lead compound demonstrates superior VAV1 degradation activity in vitro and superior efficacy in vivo
