Wu Du
Senior Vice President - Medicinal Chemistry Hinova
Seminars
Wednesday 28th January 2026
Discovery of Novel VAV1 Molecular Glue Degrader with Superior Potency & Efficacy
4:00 pm
- VAV1 is an emerging first in class target for a broad range of autoimmune and inflammatory diseases
- Discovery a class of orally available VAV1 degrader with a novel scaffold
- Lead compound demonstrates superior VAV1 degradation activity in vitro and superior efficacy in vivo
