John McGee
Senior Vice President of Platform Technology Parabilis Medicines
Seminars
Thursday 29th January 2026
A Screening-First Approach to Molecular Glue Discovery: Unlocking Cooperativity Without Structural Data
12:00 pm
- Unlocking glue discovery without relying on structural information, opening new possibilities for difficult targets
- Leveraging two tandem 100M+ member library screens to move from initial binders to true cooperative molecular glues
- Ensuring conditional, cooperative activity that reduces off-target risks and enables safer non-degradation strategies
