Expanding the Molecular Glue Toolbox: Harnessing Novel E3 Ligases

• Explore innovative strategies to harness non-Cullin-based degradation mechanisms for targeted protein degradation
• Leverage structural insights to improve prediction accuracy and guide rational discovery of novel ligase-glue pairs
• Understand how bold discovery strategies and broader search spaces can accelerate breakthroughs in molecular glue therapeutics

Speakers:

Stephen Hinshaw

Assistant Professor

Stanford University